Z21

Billable

ChapterZ00–Z99

Rankcategory

Official Description

Asymptomatic human immunodeficiency virus [HIV] infection status

Metadata & Insights

•2026 ICD-10-CM Edition - Effective October 1, 2025.
•Billable/specific code (valid for reimbursement).
•Chapter 21: Factors Influencing Health Status and Contact with Health Services (Z00-Z99).

Instructional Notes

Includes

HIV positive NOS

Excludes1(Not coded here)

acquired immunodeficiency syndrome (B20)
contact with human immunodeficiency virus [HIV] (Z20.6)
exposure to human immunodeficiency virus [HIV] (Z20.6)
human immunodeficiency virus [HIV] disease (B20)
inconclusive laboratory evidence of human immunodeficiency virus [HIV] (R75)

Code First

Human immunodeficiency virus [HIV] disease complicating pregnancy, childbirth and the puerperium, if applicable (O98.7-)

Clinical Hierarchy

CH21Factors influencing health status and contact with health services (Z00-Z99)

Z20-Z29Persons with potential health hazards related to communicable diseases (Z20-Z29)

Z21Asymptomatic human immunodeficiency virus [HIV] infection status

Alphabetic Index Mentions

These are Diagnosis Index lookup paths that route to Z21. Use them as entry terms for search, then confirm final coding instructions in the Tabular List and notes above.

7 raw paths

HIV1 unique routes

positive, seropositive→Z21

Human1 unique routes

immunodeficiency virus (HIV) disease (infection)

asymptomatic status→Z21

Status (post)1 unique routes

human immunodeficiency virus (HIV) infection, asymptomatic→Z21

Syndrome2 unique routes

retroviral seroconversion (acute)→Z21

seroconversion, retroviral (acute)→Z21

Test, tests, testing (for)2 unique routes