Is ICD-10-CM code QA0.0149 billable?

Yes, QA0.0149 (Neurodevelopmental disorder, related to pathogenic variant in other synapse related gene) is a billable ICD-10-CM diagnosis code, valid for reimbursement on HIPAA-covered transactions for FY2027.

Is QA0.0149 exempt from POA reporting?

Yes, QA0.0149 is on the CMS list of ICD-10-CM codes exempt from Present On Admission (POA) reporting for FY2027. Inpatient claims do not require a POA indicator for this code.

What chapter does ICD-10-CM code QA0.0149 belong to?

QA0.0149 belongs to Chapter 17 of the ICD-10-CM tabular list: Q00–Q99 (Congenital Malformations, Deformations and Chromosomal Abnormalities).

QA0.0149BillableCC No HCC POA Exempt

Neurodevelopmental disorder, related to pathogenic variant in other synapse related gene

Congenital Malformations, Deformations and Chromosomal Abnormalities·Neurodevelopmental disorders, related to pathogenic variants in synapse related genes·subcategory·FY 2027

Also indexed as: Disorder, neurodevelopmental, other, synapse related gene; Synaptopathy, specified NEC

Instructional notes

Includes: conditions that are coded here

Other genetic synaptopathy

Also applies, from QA0: Neurodevelopmental disorders related to specific genetic pathogenic variants

These notes sit on QA0 and apply to every code under it, including QA0.0149.

Code also: add a code for this too, order depends on the encounter

if applicable, any associated conditions, such as:
attention-deficit hyperactivity disorders (F90.-)
autism spectrum disorder (F84.0)
developmental and epileptic encephalopathy (G93.45)
epilepsy, by specific type (G40.-)
intellectual disabilities (F70-F79)
pervasive developmental disorders (F84.-)

Where QA0.0149 sits

QA0-QA1 Genetic disorders, not elsewhere classified (QA0-QA1)
QA0 Neurodevelopmental disorders related to specific genetic pathogenic variants
QA0.0 Neurodevelopmental disorders related to pathogenic variants in specific genes
QA0.01 Neurodevelopmental disorders related to pathogenic variants in certain specific genes
QA0.014 Neurodevelopmental disorders, related to pathogenic variants in synapse related genes
QA0.0149 Neurodevelopmental disorder, related to pathogenic variant in other synapse related gene

MS-DRGs

As the principal diagnosis, this code groups to these MS-DRGs (v44.0). Which one applies depends on procedures performed, secondary diagnoses (CC/MCC), and the patient's age and discharge status.

Code history

FY 2025: replaced F89 (Unspecified disorder of psychological development)