Chapter 13

M00–M99: Diseases of the Musculoskeletal System and Connective Tissue

Diseases of the Musculoskeletal System and Connective Tissue diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)
  • arthropathic psoriasis (L40.5-)
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • compartment syndrome (traumatic) (T79.A-)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Internal Codes
  • M25.321

    Other instability, right elbow

  • M25.322

    Other instability, left elbow

  • M25.329

    Other instability, unspecified elbow

  • M25.33

    Other instability, wrist

  • M25.331

    Other instability, right wrist

  • M25.332

    Other instability, left wrist

  • M25.339

    Other instability, unspecified wrist

  • M25.34

    Other instability, hand

  • M25.341

    Other instability, right hand

  • M25.342

    Other instability, left hand

  • M25.349

    Other instability, unspecified hand

  • M25.35

    Other instability, hip

  • M25.351

    Other instability, right hip

  • M25.352

    Other instability, left hip

  • M25.359

    Other instability, unspecified hip

  • M25.36

    Other instability, knee

  • M25.361

    Other instability, right knee

  • M25.362

    Other instability, left knee

  • M25.369

    Other instability, unspecified knee

  • M25.37

    Other instability, ankle and foot

  • M25.371

    Other instability, right ankle

  • M25.372

    Other instability, left ankle

  • M25.373

    Other instability, unspecified ankle

  • M25.374

    Other instability, right foot

  • M25.375

    Other instability, left foot

  • M25.376

    Other instability, unspecified foot

  • M25.39

    Other instability, other specified joint

  • M25.4

    Effusion of joint

  • M25.40

    Effusion, unspecified joint

  • M25.41

    Effusion, shoulder

  • M25.411

    Effusion, right shoulder

  • M25.412

    Effusion, left shoulder

  • M25.419

    Effusion, unspecified shoulder

  • M25.42

    Effusion, elbow

  • M25.421

    Effusion, right elbow

  • M25.422

    Effusion, left elbow

  • M25.429

    Effusion, unspecified elbow

  • M25.43

    Effusion, wrist

  • M25.431

    Effusion, right wrist

  • M25.432

    Effusion, left wrist

  • M25.439

    Effusion, unspecified wrist

  • M25.44

    Effusion, hand

  • M25.441

    Effusion, right hand

  • M25.442

    Effusion, left hand

  • M25.449

    Effusion, unspecified hand

  • M25.45

    Effusion, hip

  • M25.451

    Effusion, right hip

  • M25.452

    Effusion, left hip

  • M25.459

    Effusion, unspecified hip

  • M25.46

    Effusion, knee

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