Chapter 13

M00–M99: Diseases of the Musculoskeletal System and Connective Tissue

Diseases of the Musculoskeletal System and Connective Tissue diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)
  • arthropathic psoriasis (L40.5-)
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • compartment syndrome (traumatic) (T79.A-)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Internal Codes
  • M48.11

    Ankylosing hyperostosis [Forestier], occipito-atlanto-axial region

  • M48.12

    Ankylosing hyperostosis [Forestier], cervical region

  • M48.13

    Ankylosing hyperostosis [Forestier], cervicothoracic region

  • M48.14

    Ankylosing hyperostosis [Forestier], thoracic region

  • M48.15

    Ankylosing hyperostosis [Forestier], thoracolumbar region

  • M48.16

    Ankylosing hyperostosis [Forestier], lumbar region

  • M48.17

    Ankylosing hyperostosis [Forestier], lumbosacral region

  • M48.18

    Ankylosing hyperostosis [Forestier], sacral and sacrococcygeal region

  • M48.19

    Ankylosing hyperostosis [Forestier], multiple sites in spine

  • M48.20

    Kissing spine, site unspecified

  • M48.21

    Kissing spine, occipito-atlanto-axial region

  • M48.22

    Kissing spine, cervical region

  • M48.23

    Kissing spine, cervicothoracic region

  • M48.24

    Kissing spine, thoracic region

  • M48.25

    Kissing spine, thoracolumbar region

  • M48.26

    Kissing spine, lumbar region

  • M48.27

    Kissing spine, lumbosacral region

  • M48.30

    Traumatic spondylopathy, site unspecified

  • M48.31

    Traumatic spondylopathy, occipito-atlanto-axial region

  • M48.32

    Traumatic spondylopathy, cervical region

  • M48.33

    Traumatic spondylopathy, cervicothoracic region

  • M48.34

    Traumatic spondylopathy, thoracic region

  • M48.35

    Traumatic spondylopathy, thoracolumbar region

  • M48.36

    Traumatic spondylopathy, lumbar region

  • M48.37

    Traumatic spondylopathy, lumbosacral region

  • M48.38

    Traumatic spondylopathy, sacral and sacrococcygeal region

  • M48.40

    Fatigue fracture of vertebra, site unspecified

  • M48.40XA

    Fatigue fracture of vertebra, site unspecified, initial encounter for fracture

  • M48.40XD

    Fatigue fracture of vertebra, site unspecified, subsequent encounter for fracture with routine healing

  • M48.40XG

    Fatigue fracture of vertebra, site unspecified, subsequent encounter for fracture with delayed healing

  • M48.40XS

    Fatigue fracture of vertebra, site unspecified, sequela of fracture

  • M48.41

    Fatigue fracture of vertebra, occipito-atlanto-axial region

  • M48.41XA

    Fatigue fracture of vertebra, occipito-atlanto-axial region, initial encounter for fracture

  • M48.41XD

    Fatigue fracture of vertebra, occipito-atlanto-axial region, subsequent encounter for fracture with routine healing

  • M48.41XG

    Fatigue fracture of vertebra, occipito-atlanto-axial region, subsequent encounter for fracture with delayed healing

  • M48.41XS

    Fatigue fracture of vertebra, occipito-atlanto-axial region, sequela of fracture

  • M48.42

    Fatigue fracture of vertebra, cervical region

  • M48.42XA

    Fatigue fracture of vertebra, cervical region, initial encounter for fracture

  • M48.42XD

    Fatigue fracture of vertebra, cervical region, subsequent encounter for fracture with routine healing

  • M48.42XG

    Fatigue fracture of vertebra, cervical region, subsequent encounter for fracture with delayed healing

  • M48.42XS

    Fatigue fracture of vertebra, cervical region, sequela of fracture

  • M48.43

    Fatigue fracture of vertebra, cervicothoracic region

  • M48.43XA

    Fatigue fracture of vertebra, cervicothoracic region, initial encounter for fracture

  • M48.43XD

    Fatigue fracture of vertebra, cervicothoracic region, subsequent encounter for fracture with routine healing

  • M48.43XG

    Fatigue fracture of vertebra, cervicothoracic region, subsequent encounter for fracture with delayed healing

  • M48.43XS

    Fatigue fracture of vertebra, cervicothoracic region, sequela of fracture

  • M48.44

    Fatigue fracture of vertebra, thoracic region

  • M48.44XA

    Fatigue fracture of vertebra, thoracic region, initial encounter for fracture

  • M48.44XD

    Fatigue fracture of vertebra, thoracic region, subsequent encounter for fracture with routine healing

  • M48.44XG

    Fatigue fracture of vertebra, thoracic region, subsequent encounter for fracture with delayed healing

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