Chapter 13

M00–M99: Diseases of the Musculoskeletal System and Connective Tissue

Diseases of the Musculoskeletal System and Connective Tissue diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)
  • arthropathic psoriasis (L40.5-)
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • compartment syndrome (traumatic) (T79.A-)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Internal Codes
  • M33.19

    Other dermatomyositis with other organ involvement

  • M33.20

    Polymyositis, organ involvement unspecified

  • M33.21

    Polymyositis with respiratory involvement

  • M33.22

    Polymyositis with myopathy

  • M33.29

    Polymyositis with other organ involvement

  • M33.90

    Dermatopolymyositis, unspecified, organ involvement unspecified

  • M33.91

    Dermatopolymyositis, unspecified with respiratory involvement

  • M33.92

    Dermatopolymyositis, unspecified with myopathy

  • M33.93

    Dermatopolymyositis, unspecified without myopathy

  • M33.99

    Dermatopolymyositis, unspecified with other organ involvement

  • M34.0

    Progressive systemic sclerosis

  • M34.1

    CR(E)ST syndrome

  • M34.2

    Systemic sclerosis induced by drug and chemical

  • M34.81

    Systemic sclerosis with lung involvement

  • M34.82

    Systemic sclerosis with myopathy

  • M34.83

    Systemic sclerosis with polyneuropathy

  • M34.89

    Other systemic sclerosis

  • M34.9

    Systemic sclerosis, unspecified

  • M35.00

    Sjögren syndrome, unspecified

  • M35.01

    Sjögren syndrome with keratoconjunctivitis

  • M35.02

    Sjögren syndrome with lung involvement

  • M35.03

    Sjögren syndrome with myopathy

  • M35.04

    Sjögren syndrome with tubulo-interstitial nephropathy

  • M35.05

    Sjögren syndrome with inflammatory arthritis

  • M35.06

    Sjögren syndrome with peripheral nervous system involvement

  • M35.07

    Sjögren syndrome with central nervous system involvement

  • M35.08

    Sjögren syndrome with gastrointestinal involvement

  • M35.09

    Sjögren syndrome with other organ involvement

  • M35.0A

    Sjögren syndrome with glomerular disease

  • M35.0B

    Sjögren syndrome with vasculitis

  • M35.0C

    Sjögren syndrome with dental involvement

  • M35.1

    Other overlap syndromes

  • M35.2

    Behçet's disease

  • M35.3

    Polymyalgia rheumatica

  • M35.4

    Diffuse (eosinophilic) fasciitis

  • M35.5

    Multifocal fibrosclerosis

  • M35.6

    Relapsing panniculitis [Weber-Christian]

  • M35.7

    Hypermobility syndrome

  • M35.81

    Multisystem inflammatory syndrome

  • M35.89

    Other specified systemic involvement of connective tissue

  • M35.9

    Systemic involvement of connective tissue, unspecified

  • M36.0

    Dermato(poly)myositis in neoplastic disease

  • M36.1

    Arthropathy in neoplastic disease

  • M36.2

    Hemophilic arthropathy

  • M36.3

    Arthropathy in other blood disorders

  • M36.4

    Arthropathy in hypersensitivity reactions classified elsewhere

  • M36.8

    Systemic disorders of connective tissue in other diseases classified elsewhere

  • M40.00

    Postural kyphosis, site unspecified

  • M40.03

    Postural kyphosis, cervicothoracic region

  • M40.04

    Postural kyphosis, thoracic region

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