Chapter 13

M00–M99: Diseases of the Musculoskeletal System and Connective Tissue

Diseases of the Musculoskeletal System and Connective Tissue diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)
  • arthropathic psoriasis (L40.5-)
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • compartment syndrome (traumatic) (T79.A-)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Internal Codes
  • M27.3

    Alveolitis of jaws

  • M27.40

    Unspecified cyst of jaw

  • M27.49

    Other cysts of jaw

  • M27.51

    Perforation of root canal space due to endodontic treatment

  • M27.52

    Endodontic overfill

  • M27.53

    Endodontic underfill

  • M27.59

    Other periradicular pathology associated with previous endodontic treatment

  • M27.61

    Osseointegration failure of dental implant

  • M27.62

    Post-osseointegration biological failure of dental implant

  • M27.63

    Post-osseointegration mechanical failure of dental implant

  • M27.69

    Other endosseous dental implant failure

  • M27.8

    Other specified diseases of jaws

  • M27.9

    Disease of jaws, unspecified

  • M30.0

    Polyarteritis nodosa

  • M30.1

    Polyarteritis with lung involvement [Churg-Strauss]

  • M30.2

    Juvenile polyarteritis

  • M30.3

    Mucocutaneous lymph node syndrome [Kawasaki]

  • M30.8

    Other conditions related to polyarteritis nodosa

  • M31.0

    Hypersensitivity angiitis

  • M31.10

    Thrombotic microangiopathy, unspecified

  • M31.11

    Hematopoietic stem cell transplantation-associated thrombotic microangiopathy [HSCT-TMA]

  • M31.19

    Other thrombotic microangiopathy

  • M31.2

    Lethal midline granuloma

  • M31.30

    Wegener's granulomatosis without renal involvement

  • M31.31

    Wegener's granulomatosis with renal involvement

  • M31.4

    Aortic arch syndrome [Takayasu]

  • M31.5

    Giant cell arteritis with polymyalgia rheumatica

  • M31.6

    Other giant cell arteritis

  • M31.7

    Microscopic polyangiitis

  • M31.8

    Other specified necrotizing vasculopathies

  • M31.9

    Necrotizing vasculopathy, unspecified

  • M32.0

    Drug-induced systemic lupus erythematosus

  • M32.10

    Systemic lupus erythematosus, organ or system involvement unspecified

  • M32.11

    Endocarditis in systemic lupus erythematosus

  • M32.12

    Pericarditis in systemic lupus erythematosus

  • M32.13

    Lung involvement in systemic lupus erythematosus

  • M32.14

    Glomerular disease in systemic lupus erythematosus

  • M32.15

    Tubulo-interstitial nephropathy in systemic lupus erythematosus

  • M32.19

    Other organ or system involvement in systemic lupus erythematosus

  • M32.8

    Other forms of systemic lupus erythematosus

  • M32.9

    Systemic lupus erythematosus, unspecified

  • M33.00

    Juvenile dermatomyositis, organ involvement unspecified

  • M33.01

    Juvenile dermatomyositis with respiratory involvement

  • M33.02

    Juvenile dermatomyositis with myopathy

  • M33.03

    Juvenile dermatomyositis without myopathy

  • M33.09

    Juvenile dermatomyositis with other organ involvement

  • M33.10

    Other dermatomyositis, organ involvement unspecified

  • M33.11

    Other dermatomyositis with respiratory involvement

  • M33.12

    Other dermatomyositis with myopathy

  • M33.13

    Other dermatomyositis without myopathy

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