E34.321

Billable
ChapterE00–E89
Ranksubcategory
Official Description

Primary insulin-like growth factor-1 (IGF-1) deficiency

Metadata & Insights
  • Billable/specific code (valid for reimbursement).
  • Chapter 4: Endocrine, Nutritional and Metabolic Diseases (E00-E89).

Instructional Notes

Includes
  • Acid-labile subunit gene (IGFALS) defect
  • Growth hormone gene 1 (GH1) defect with growth hormone neutralizing antibodies
  • Growth hormone insensitivity syndrome (GHIS)
  • Insulin-like growth factor 1 gene (IGF1) defect
  • Laron type short stature
  • Severe primary insulin-like growth factor-1 deficiency (SPIGFD)
  • Signal transducer and activator of transcription 5B gene (STAT5b) defect
General instructions are available for the parent sections:

Clinical Hierarchy

BillableHas subcodes
CH4Endocrine, nutritional and metabolic diseases (E00-E89)
E20-E35Disorders of other endocrine glands (E20-E35)
E34Other endocrine disorders
E34.3Short stature due to endocrine disorder
E34.32Genetic causes of short stature
E34.321Primary insulin-like growth factor-1 (IGF-1) deficiencyBillable

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to E34.321:

subcategoryE34.3
Short stature due to endocrine disorder
View context instructions
categoryE34
Other endocrine disorders
View context instructions
blockE20-E35
Disorders of other endocrine glands (E20-E35)
View context instructions
chapterCH4
Endocrine, nutritional and metabolic diseases (E00-E89)
View context instructions

Code History

  • FY 2022: This code replaced E34.3 (Short stature due to endocrine disorder)

MS-DRG Classification

2026 v43.1

This code is grouped within the following Diagnosis Related Group(s) for clinical reimbursement:

Cross Reference

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