D59.4

Billable
ChapterD50–D89
Ranksubcategory
Official Description

Other nonautoimmune hemolytic anemias

Metadata & Insights
  • •2026 ICD-10-CM Edition - Effective October 1, 2025.
  • •Billable/specific code (valid for reimbursement).
  • •Chapter 3: Diseases of the Blood and Blood-Forming Organs (D50-D89).

Instructional Notes

Includes
  • Mechanical hemolytic anemia
  • Microangiopathic hemolytic anemia
  • Toxic hemolytic anemia
General instructions are available for the parent sections:
View CH3 Notes

Clinical Hierarchy

CH3Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
D55-D59Hemolytic anemias (D55-D59)
D59Acquired hemolytic anemia
D59.4Other nonautoimmune hemolytic anemias

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to D59.4:

chapterCH3
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
View context instructions

Alphabetic Index Mentions

These are Diagnosis Index lookup paths that route to D59.4. Use them as entry terms for search, then confirm final coding instructions in the Tabular List and notes above.

13 raw paths
Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)10 unique routes
hemolytic(10 variants)
acquired(2 variants)
infectious→D59.4
toxic→D59.4
due to(2 variants)
cardiac conditions→D59.4
presence of shunt or other internal prosthetic device→D59.4
mechanical→D59.4
microangiopathic→D59.4
nonautoimmune→D59.4
secondary→D59.4
symptomatic→D59.4
toxic→D59.4
Disease, diseased1 unique routes
nonautoimmune hemolytic→D59.4
Nonautoimmune hemolytic anemia1 unique routes
Direct index entry→D59.4
Syndrome1 unique routes
erythrocyte fragmentation→D59.4

MS-DRG Classification

2026 v43.1

This code is grouped within the following Diagnosis Related Group(s) for clinical reimbursement:

DRG 791
Prematurity with Major Problems
DRG 793
Full Term Neonate with Major Problems
DRG 808
Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with MCC
DRG 809
Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with CC
DRG 810
Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders without CC/MCC

Cross Reference

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