Chapter 2

C00–D49: Neoplasms

Neoplasms diagnostic classification updated for 2026.

Internal Codes
  • D44.2|

    Neoplasm of uncertain behavior of parathyroid gland

  • D44.3|

    Neoplasm of uncertain behavior of pituitary gland

  • D44.4|

    Neoplasm of uncertain behavior of craniopharyngeal duct

  • D44.5|

    Neoplasm of uncertain behavior of pineal gland

  • D44.6|

    Neoplasm of uncertain behavior of carotid body

  • D44.7|

    Neoplasm of uncertain behavior of aortic body and other paraganglia

  • D44.9|

    Neoplasm of uncertain behavior of unspecified endocrine gland

  • D45|

    Polycythemia vera

  • D46|

    Myelodysplastic syndromes

  • D46.0|

    Refractory anemia without ring sideroblasts, so stated

  • D46.1|

    Refractory anemia with ring sideroblasts

  • D46.2|

    Refractory anemia with excess of blasts [RAEB]

  • D46.20|

    Refractory anemia with excess of blasts, unspecified

  • D46.21|

    Refractory anemia with excess of blasts 1

  • D46.22|

    Refractory anemia with excess of blasts 2

  • D46.4|

    Refractory anemia, unspecified

  • D46.9|

    Myelodysplastic syndrome, unspecified

  • D46.A|

    Refractory cytopenia with multilineage dysplasia

  • D46.B|

    Refractory cytopenia with multilineage dysplasia and ring sideroblasts

  • D46.C|

    Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality

  • D46.Z|

    Other myelodysplastic syndromes

  • D47|

    Other neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue

  • D47.0|

    Mast cell neoplasms of uncertain behavior

  • D47.01|

    Cutaneous mastocytosis

  • D47.02|

    Systemic mastocytosis

  • D47.09|

    Other mast cell neoplasms of uncertain behavior

  • D47.1|

    Chronic myeloproliferative disease

  • D47.2|

    Monoclonal gammopathy

  • D47.3|

    Essential (hemorrhagic) thrombocythemia

  • D47.4|

    Osteomyelofibrosis

  • D47.9|

    Neoplasm of uncertain behavior of lymphoid, hematopoietic and related tissue, unspecified

  • D47.Z|

    Other specified neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue

  • D47.Z1|

    Post-transplant lymphoproliferative disorder (PTLD)

  • D47.Z2|

    Castleman disease

  • D47.Z9|

    Other specified neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue

  • D48|

    Neoplasm of uncertain behavior of other and unspecified sites

  • D48.0|

    Neoplasm of uncertain behavior of bone and articular cartilage

  • D48.1|

    Neoplasm of uncertain behavior of connective and other soft tissue

  • D48.11|

    Desmoid tumor

  • D48.110|

    Desmoid tumor of head and neck

  • D48.111|

    Desmoid tumor of chest wall

  • D48.112|

    Desmoid tumor, intrathoracic

  • D48.113|

    Desmoid tumor of abdominal wall

  • D48.114|

    Desmoid tumor, intraabdominal

  • D48.115|

    Desmoid tumor of upper extremity and shoulder girdle

  • D48.116|

    Desmoid tumor of lower extremity and pelvic girdle

  • D48.117|

    Desmoid tumor of back

  • D48.118|

    Desmoid tumor of other site

  • D48.119|

    Desmoid tumor of unspecified site

  • D48.19|

    Other specified neoplasm of uncertain behavior of connective and other soft tissue

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