D48Not billable, use a more specific code below
Neoplasm of uncertain behavior of other and unspecified sites
In Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48), chapter 2: Neoplasms
21 billable codes under D48: none are a CC or MCC; none map to an HCC.
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Instructional notes
Excludes1: not coded here, use a different code
- neurofibromatosis (nonmalignant) (Q85.0-)
Also applies, from Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)
These notes sit on D37-D48 and apply to every code under it, including D48.
Excludes1: not coded here, use a different code
- neoplasms of unspecified behavior (D49.-)
Official coding guidelines
From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.
Rules for coding benign and malignant neoplasms: using the Neoplasm Table, sequencing primary and secondary sites, treatment encounters, complications, and current cancer versus personal history.
- Admission/Encounter for treatment of primary site (page 33)
- Admission/Encounter for treatment of secondary site (page 33)
- Coding and sequencing of complications (page 34)
- Primary malignancy previously excised (page 34)
- Admissions/Encounters involving antineoplastic chemotherapy, immunotherapy and radiation therapy (page 35)
- Admission/encounter to determine extent of malignancy (page 36)
- Symptoms, signs, and abnormal findings listed in Chapter 18 associated with neoplasms (page 36)
- Admission/encounter for pain control/management (page 36)
All codes under D48
D48 can't be used on a claim. Pick a billable code below; grey headings group them.
- D48.0Neoplasm of uncertain behavior of bone and articular cartilage
- D48.1Neoplasm of uncertain behavior of connective and other soft tissue
- D48.11Desmoid tumor
- D48.110Desmoid tumor of head and neck
- D48.111Desmoid tumor of chest wall
- D48.112Desmoid tumor, intrathoracic
- D48.113Desmoid tumor of abdominal wall
- D48.114Desmoid tumor, intraabdominal
- D48.115Desmoid tumor of upper extremity and shoulder girdle
- D48.116Desmoid tumor of lower extremity and pelvic girdle
- D48.117Desmoid tumor of back
- D48.118Desmoid tumor of other site
- D48.119Desmoid tumor of unspecified site
- D48.19Other specified neoplasm of uncertain behavior of connective and other soft tissue
- D48.2Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system
- D48.3Neoplasm of uncertain behavior of retroperitoneum
- D48.4Neoplasm of uncertain behavior of peritoneum
- D48.5Neoplasm of uncertain behavior of skin
- D48.6Neoplasm of uncertain behavior of breast
- D48.60Neoplasm of uncertain behavior of unspecified breast
- D48.61Neoplasm of uncertain behavior of right breast
- D48.62Neoplasm of uncertain behavior of left breast
- D48.7Neoplasm of uncertain behavior of other specified sites
- D48.9Neoplasm of uncertain behavior, unspecified
D48 MS-DRGs
As the principal diagnosis, the billable codes under D48 group to these 27 MS-DRGs (v44.0). Which one applies depends on procedures performed, secondary diagnoses (CC/MCC), and the patient's age and discharge status.
- DRG 564 Other Musculoskeletal System and Connective Tissue Diagnoses with MCC (12 of 21 codes)
- DRG 565 Other Musculoskeletal System and Connective Tissue Diagnoses with CC (12 of 21 codes)
- DRG 566 Other Musculoskeletal System and Connective Tissue Diagnoses without CC/MCC (12 of 21 codes)
- DRG 582 Mastectomy for Malignancy with CC/MCC (3 of 21 codes)
- DRG 583 Mastectomy for Malignancy without CC/MCC (3 of 21 codes)
- DRG 597 Malignant Breast Disorders with MCC (3 of 21 codes)
- DRG 598 Malignant Breast Disorders with CC (3 of 21 codes)
- DRG 599 Malignant Breast Disorders without CC/MCC (3 of 21 codes)
- DRG 374 Digestive Malignancy with MCC (2 of 21 codes)
- DRG 375 Digestive Malignancy with CC (2 of 21 codes)
- DRG 376 Digestive Malignancy without CC/MCC (2 of 21 codes)
- DRG 826 Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures with MCC (2 of 21 codes)
- DRG 827 Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures with CC (2 of 21 codes)
- DRG 828 Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Major O.R. Procedures without CC/MCC (2 of 21 codes)
- DRG 829 Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Other Procedures with CC/MCC (2 of 21 codes)
- DRG 830 Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Other Procedures without CC/MCC (2 of 21 codes)
- DRG 843 Other Myeloproliferative Disorders or Poorly Differentiated Neoplastic Diagnoses with MCC (2 of 21 codes)
- DRG 844 Other Myeloproliferative Disorders or Poorly Differentiated Neoplastic Diagnoses with CC (2 of 21 codes)
- DRG 845 Other Myeloproliferative Disorders or Poorly Differentiated Neoplastic Diagnoses without CC/MCC (2 of 21 codes)
- DRG 456 Spinal Fusion Except Cervical with Spinal Curvature, Malignancy, or Infection with MCC (1 of 21 codes)
- DRG 457 Spinal Fusion Except Cervical with Spinal Curvature, Malignancy, or Infection with CC (1 of 21 codes)
- DRG 458 Spinal Fusion Except Cervical with Spinal Curvature, Malignancy, or Infection without CC/MCC (1 of 21 codes)
- DRG 542 Pathological Fractures and Musculoskeletal and Connective Tissue Malignancy with MCC (1 of 21 codes)
- DRG 543 Pathological Fractures and Musculoskeletal and Connective Tissue Malignancy with CC (1 of 21 codes)
- DRG 544 Pathological Fractures and Musculoskeletal and Connective Tissue Malignancy without CC/MCC (1 of 21 codes)
- DRG 606 Minor Skin Disorders with MCC (1 of 21 codes)
- DRG 607 Minor Skin Disorders without MCC (1 of 21 codes)
Other codes that refer to D48
Notes on these codes point to D48.
Code history
Valid since FY2016, when ICD-10-CM took effect on October 1, 2015. No changes since.