Is ICD-10-CM code B25 billable?

No, B25 (Cytomegaloviral disease) is a non-billable ICD-10-CM code. It must be coded to a more specific subcategory before it can be used for reimbursement.

What chapter does ICD-10-CM code B25 belong to?

B25 belongs to Chapter 1 of the ICD-10-CM tabular list: A00–B99 (Certain Infectious and Parasitic Diseases).

B25Not billable, use a more specific code below

Cytomegaloviral disease

In Other viral diseases (B25-B34), chapter 1: Certain Infectious and Parasitic Diseases

5 billable codes under B25: 2 are an MCC, 3 are a CC; all map to HCC 6 (Opportunistic Infections).A CC or MCC (major CC) is a secondary diagnosis that raises the MS-DRG payment. An HCC counts toward a Medicare Advantage patient's risk score.

Instructional notes

Excludes1: not coded here, use a different code

congenital cytomegalovirus infection (P35.1)
cytomegaloviral mononucleosis (B27.1-)

Official coding guidelines

From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.

Rules for coding infections and parasitic diseases, including HIV, organism and drug resistance codes, sepsis and septic shock, MRSA, Zika, and COVID-19.

Human Immunodeficiency Virus (HIV) Infections (page 19)
Infectious agents as the cause of diseases classified to other chapters (page 22)
Infections resistant to antibiotics (page 22)
Sepsis, Severe Sepsis, and Septic Shock (page 23)
Methicillin Resistant Staphylococcus aureus (MRSA) Conditions (page 27)
Zika virus infections (page 28)
Coronavirus infections (page 28)

Read Section I.C.1 (page 19)

All codes under B25

B25 can't be used on a claim. Pick a billable code below; grey headings group them.

B25 MS-DRGs

As the principal diagnosis, the billable codes under B25 group to these 16 MS-DRGs (v44.0). Which one applies depends on procedures performed, secondary diagnoses (CC/MCC), and the patient's age and discharge status.

DRG 865 Viral Illness with MCC (2 of 5 codes)
DRG 866 Viral Illness without MCC (2 of 5 codes)
DRG 974 HIV with Major Related Condition with MCC (2 of 5 codes)
DRG 975 HIV with Major Related Condition with CC (2 of 5 codes)
DRG 976 HIV with Major Related Condition without CC/MCC (2 of 5 codes)
DRG 177 Respiratory Infections and Inflammations with MCC (1 of 5 codes)
DRG 178 Respiratory Infections and Inflammations with CC (1 of 5 codes)
DRG 179 Respiratory Infections and Inflammations without CC/MCC (1 of 5 codes)
DRG 438 Disorders of Pancreas Except Malignancy with MCC (1 of 5 codes)
DRG 439 Disorders of Pancreas Except Malignancy with CC (1 of 5 codes)
DRG 440 Disorders of Pancreas Except Malignancy without CC/MCC (1 of 5 codes)
DRG 441 Disorders of Liver Except Malignancy, Cirrhosis or Alcoholic Hepatitis with MCC (1 of 5 codes)
DRG 442 Disorders of Liver Except Malignancy, Cirrhosis or Alcoholic Hepatitis with CC (1 of 5 codes)
DRG 443 Disorders of Liver Except Malignancy, Cirrhosis or Alcoholic Hepatitis without CC/MCC (1 of 5 codes)
DRG 791 Prematurity with Major Problems (1 of 5 codes)
DRG 793 Full Term Neonate with Major Problems (1 of 5 codes)

Other codes that refer to B25

Notes on these codes point to B25.

B10 Excludes2: human herpesvirus 5 (B25.-)
O98.5 Includes: Conditions in A80-B09, B25-B34, R87.81-, R87.82-
T86.43 Use Additional Code: Cytomegalovirus (CMV) infection (B25.-)
Z83.1 Includes: Conditions classifiable to A00-B19, B25-B94, B99

About the condition

Plain-language background from MedlinePlus (National Library of Medicine), not coding guidance.

Cytomegalovirus Infections

Cytomegalovirus (CMV) is a virus found around the world. It is related to the viruses that cause chickenpox and infectious mononucleosis (mono). Between 50% and 80% of adults in the United States have had a CMV infection by age 40. Once CMV is in a person's body, it stays there for life.

Code history

Valid since FY2016, when ICD-10-CM took effect on October 1, 2015. No changes since.