A41Not billable, use a more specific code below

Other sepsis

In Other bacterial diseases (A30-A49), chapter 1: Certain Infectious and Parasitic Diseases

15 billable codes under A41: all are an MCC; all map to HCC 2 (Septicemia, Sepsis, Systemic Inflammatory Response Syndrome/Shock).A CC or MCC (major CC) is a secondary diagnosis that raises the MS-DRG payment. An HCC counts toward a Medicare Advantage patient's risk score.

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Instructional notes

Excludes1: not coded here, use a different code

  • bacteremia NOS (R78.81)
  • neonatal (P36.-)
  • puerperal sepsis (O85)
  • streptococcal sepsis (A40.-)

Excludes2: not included here, code separately if applicable

  • sepsis (due to) (in) actinomycotic (A42.7)
  • sepsis (due to) (in) anthrax (A22.7)
  • sepsis (due to) (in) candidal (B37.7)
  • sepsis (due to) (in) Erysipelothrix (A26.7)
  • sepsis (due to) (in) extraintestinal yersiniosis (A28.2)
  • sepsis (due to) (in) gonococcal (A54.86)
  • sepsis (due to) (in) herpesviral (B00.7)
  • sepsis (due to) (in) listerial (A32.7)
  • sepsis (due to) (in) melioidosis (A24.1)
  • sepsis (due to) (in) meningococcal (A39.2-A39.4)
  • sepsis (due to) (in) plague (A20.7)
  • sepsis (due to) (in) tularemia (A21.7)
  • toxic shock syndrome (A48.3)

Code first: code the underlying condition first, then this code

  • if applicable, postprocedural sepsis (T81.44-)
  • sepsis due to central venous catheter (T80.211-)
  • sepsis during labor (O75.3)
  • sepsis following abortion, ectopic or molar pregnancy (O03.37, O03.87, O04.87, O07.37, O08.82)
  • sepsis following immunization (T88.0-)
  • sepsis following infusion, transfusion or therapeutic injection (T80.22-, T80.29-)

Official coding guidelines

From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.

  • Section I.C.1.d Sepsis, Severe Sepsis, and Septic Shock (page 23), covers A41

    Code the underlying systemic infection first (A41.9 if unspecified), then a code from R65.2 only when severe sepsis or related acute organ dysfunction is documented, plus organ dysfunction codes. R65.2 codes can never be principal diagnosis.

Other Chapter 1 topics:

Read Section I.C.1 (page 19)

Other codes that refer to A41

Notes on these codes point to A41.

  • I5A Code First: sepsis (A41.-)
  • J95.02 Use Additional Code: sepsis (A40, A41.-)
  • K94.02 Use Additional Code: sepsis (A40.-, A41.-)
  • K94.12 Use Additional Code: sepsis (A40.-, A41.-)
  • K94.22 Use Additional Code: sepsis (A40.-, A41.-)
  • K95.01 Use Additional Code: sepsis (A40.-, A41.-)
  • K95.81 Use Additional Code: sepsis (A40.-, A41.-)

About the condition

Plain-language background from MedlinePlus (National Library of Medicine), not coding guidance.

Sepsis

Sepsis is your body's overactive and extreme response to an infection. Sepsis is a life-threatening medical emergency. Without quick treatment, it can lead to tissue damage, organ failure, and even death.

Read more about sepsis on MedlinePlus

Code history

Valid since FY2016, when ICD-10-CM took effect on October 1, 2015. No changes since.