HCC 114 (V28)

Common Variable and Combined Immunodeficiencies

18 ICD-10-CM codes map to this category in the CMS-HCC V28 risk adjustment model for payment year 2027. All 115 HCCs

D81.0Severe combined immunodeficiency [SCID] with reticular dysgenesis
D81.1Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
D81.2Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
D81.30Adenosine deaminase deficiency, unspecified
D81.31Severe combined immunodeficiency due to adenosine deaminase deficiency
D81.32Adenosine deaminase 2 deficiency
D81.39Other adenosine deaminase deficiency
D81.5Purine nucleoside phosphorylase [PNP] deficiency
D81.6Major histocompatibility complex class I deficiency
D81.7Major histocompatibility complex class II deficiency
D81.82Activated Phosphoinositide 3-kinase Delta Syndrome [APDS]
D81.89Other combined immunodeficiencies
D81.9Combined immunodeficiency, unspecified
D83.0Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
D83.1Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
D83.2Common variable immunodeficiency with autoantibodies to B- or T-cells
D83.8Other common variable immunodeficiencies
D83.9Common variable immunodeficiency, unspecified