Allergy status to drugs, medicaments and biological substances
In Persons with potential health hazards related to family and personal history and certain conditions influencing health status (Z77-Z99), chapter 21: Factors Influencing Health Status and Contact with Health Services
10 billable codes under Z88: none are a CC or MCC; none map to an HCC.
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Instructional notes
Excludes2: not included here, code separately if applicable
- Allergy status, other than to drugs and biological substances (Z91.0-)
Also applies, from Persons with potential health hazards related to family and personal history and certain conditions influencing health status (Z77-Z99)
These notes sit on Z77-Z99 and apply to every code under it, including Z88.
Code also: add a code for this too, order depends on the encounter
- any follow-up examination (Z08-Z09)
Official coding guidelines
From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.
Covers when and how to use Z codes (Z00-Z99) for encounters and supplementary information, including contact, status, history, screening, aftercare, exams, and social determinants of health.
All codes under Z88
Z88 can't be used on a claim. Pick a billable code below; grey headings group them.
- Z88.0Allergy status to penicillin
- Z88.1Allergy status to other antibiotic agents
- Z88.2Allergy status to sulfonamides
- Z88.3Allergy status to other anti-infective agents
- Z88.4Allergy status to anesthetic agent
- Z88.5Allergy status to narcotic agent
- Z88.6Allergy status to analgesic agent
- Z88.7Allergy status to serum and vaccine
- Z88.8Allergy status to other drugs, medicaments and biological substances
- Z88.9Allergy status to unspecified drugs, medicaments and biological substances
Z88 MS-DRG
As the principal diagnosis, all 10 billable codes under Z88 group to MS-DRG 951 (v44.0).
Other codes that refer to Z88
Notes on these codes point to Z88.
About the condition
Plain-language background from MedlinePlus (National Library of Medicine), not coding guidance.
Antibiotics
Antibiotics are medicines that fight bacterial infections in people and animals. They work by killing the bacteria or by making it hard for the bacteria to grow and multiply.
Read more about antibiotics on MedlinePlusDrug Reactions
Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.
Read more about drug reactions on MedlinePlusCode history
Valid since FY2016, when ICD-10-CM took effect on October 1, 2015. No changes since.
