Is ICD-10-CM code Z16 billable?

No, Z16 (Resistance to antimicrobial drugs) is a non-billable ICD-10-CM code. It must be coded to a more specific subcategory before it can be used for reimbursement.

What chapter does ICD-10-CM code Z16 belong to?

Z16 belongs to Chapter 21 of the ICD-10-CM tabular list: Z00–Z99 (Factors Influencing Health Status and Contact with Health Services).

Z16

Non-Billable

ChapterZ00–Z99

Rankcategory

Description

Resistance to antimicrobial drugs

About ICD-10-CM code Z16

Under Z00-Z99 Factors Influencing Health Status and Contact with Health Services, ICD-10-CM code Z16 describes Resistance to antimicrobial drugs. This code cannot be billed directly because more specific child codes exist beneath it.

Use a more specific code (0 billable, 3 non-billable)

Z16.1Resistance to beta lactam antibioticshas subcodes Z16.2Resistance to other antibioticshas subcodes Z16.3Resistance to other antimicrobial drugshas subcodes

Metadata & Insights

•Non-billable category (requires more specific sub-code).
•Chapter 21: Factors Influencing Health Status and Contact with Health Services (Z00-Z99).

Instructional Notes

Excludes1(Not coded here. Use a different code.)

Methicillin resistant Staphylococcus aureus infection (A49.02)
Methicillin resistant Staphylococcus aureus pneumonia (J15.212)
Sepsis due to Methicillin resistant Staphylococcus aureus (A41.02)

Code First

the infection

Clinical Hierarchy

BillableHas subcodes

CH21Factors influencing health status and contact with health services (Z00-Z99)

Z16Resistance to antimicrobial drugsNot billable

Z16.1Resistance to beta lactam antibioticsSubcodes

Z16.2Resistance to other antibioticsSubcodes

Z16.3Resistance to other antimicrobial drugsSubcodes

MS-DRG Classification

2026

No direct MS-DRG triggers identified.

Cross Reference

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