Z15Not billable, use a more specific code below

Genetic susceptibility to disease

In Genetic carrier and genetic susceptibility to disease (Z14-Z15), chapter 21: Factors Influencing Health Status and Contact with Health Services

14 billable codes under Z15: none are a CC or MCC; none map to an HCC.

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Instructional notes

Includes: conditions that are coded here

  • confirmed abnormal gene

Excludes1: not coded here, use a different code

Use additional code: add a second code for this, listed after this one

  • code, if applicable, for any associated family history of the disease (Z80-Z84)

Official coding guidelines

From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.

Covers when and how to use Z codes (Z00-Z99) for encounters and supplementary information, including contact, status, history, screening, aftercare, exams, and social determinants of health.

Read Section I.C.21 (page 92)

Z15 MS-DRG

As the principal diagnosis, all 14 billable codes under Z15 group to MS-DRG 951 (v44.0).

Other codes that refer to Z15

Notes on these codes point to Z15.

  • Z40.0 Use Additional Code: code to identify risk factor, such as genetic susceptibility to malignant neoplasm Z15.-

Code history

Valid since FY2016, when ICD-10-CM took effect on October 1, 2015. No changes since.