Chapter 18

R00–R99: Symptoms, Signs and Abnormal Clinical and Laboratory Findings

Symptoms, Signs and Abnormal Clinical and Laboratory Findings diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)
  • abnormal findings on antenatal screening of mother (O28.-)
  • certain conditions originating in the perinatal period (P04-P96)
  • signs and symptoms classified in the body system chapters
  • signs and symptoms of breast (N63, N64.5)
Internal Codes
  • R40.2423

    Glasgow coma scale score 9-12, at hospital admission

  • R40.2424

    Glasgow coma scale score 9-12, 24 hours or more after hospital admission

  • R40.243

    Glasgow coma scale score 3-8

  • R40.2430

    Glasgow coma scale score 3-8, unspecified time

  • R40.2431

    Glasgow coma scale score 3-8, in the field [EMT or ambulance]

  • R40.2432

    Glasgow coma scale score 3-8, at arrival to emergency department

  • R40.2433

    Glasgow coma scale score 3-8, at hospital admission

  • R40.2434

    Glasgow coma scale score 3-8, 24 hours or more after hospital admission

  • R40.244

    Other coma, without documented Glasgow coma scale score, or with partial score reported

  • R40.2440

    Other coma, without documented Glasgow coma scale score, or with partial score reported, unspecified time

  • R40.2441

    Other coma, without documented Glasgow coma scale score, or with partial score reported, in the field [EMT or ambulance]

  • R40.2442

    Other coma, without documented Glasgow coma scale score, or with partial score reported, at arrival to emergency department

  • R40.2443

    Other coma, without documented Glasgow coma scale score, or with partial score reported, at hospital admission

  • R40.2444

    Other coma, without documented Glasgow coma scale score, or with partial score reported, 24 hours or more after hospital admission

  • R40.2A

    Nontraumatic coma due to underlying condition

  • R40.3

    Persistent vegetative state

  • R40.4

    Transient alteration of awareness

  • R41.0

    Disorientation, unspecified

  • R41.1

    Anterograde amnesia

  • R41.2

    Retrograde amnesia

  • R41.3

    Other amnesia

  • R41.4

    Neurologic neglect syndrome

  • R41.81

    Age-related cognitive decline

  • R41.82

    Altered mental status, unspecified

  • R41.83

    Borderline intellectual functioning

  • R41.840

    Attention and concentration deficit

  • R41.841

    Cognitive communication deficit

  • R41.842

    Visuospatial deficit

  • R41.843

    Psychomotor deficit

  • R41.844

    Frontal lobe and executive function deficit

  • R41.85

    Anosognosia

  • R41.89

    Other symptoms and signs involving cognitive functions and awareness

  • R41.9

    Unspecified symptoms and signs involving cognitive functions and awareness

  • R42

    Dizziness and giddiness

  • R43.0

    Anosmia

  • R43.1

    Parosmia

  • R43.2

    Parageusia

  • R43.8

    Other disturbances of smell and taste

  • R43.9

    Unspecified disturbances of smell and taste

  • R44.0

    Auditory hallucinations

  • R44.1

    Visual hallucinations

  • R44.2

    Other hallucinations

  • R44.3

    Hallucinations, unspecified

  • R44.8

    Other symptoms and signs involving general sensations and perceptions

  • R44.9

    Unspecified symptoms and signs involving general sensations and perceptions

  • R45.0

    Nervousness

  • R45.1

    Restlessness and agitation

  • R45.2

    Unhappiness

  • R45.3

    Demoralization and apathy

  • R45.4

    Irritability and anger

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