Chapter 18

R00–R99: Symptoms, Signs and Abnormal Clinical and Laboratory Findings

Symptoms, Signs and Abnormal Clinical and Laboratory Findings diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)
  • abnormal findings on antenatal screening of mother (O28.-)
  • certain conditions originating in the perinatal period (P04-P96)
  • signs and symptoms classified in the body system chapters
  • signs and symptoms of breast (N63, N64.5)
Internal Codes
  • R40.2251

    Coma scale, best verbal response, oriented, in the field [EMT or ambulance]

  • R40.2252

    Coma scale, best verbal response, oriented, at arrival to emergency department

  • R40.2253

    Coma scale, best verbal response, oriented, at hospital admission

  • R40.2254

    Coma scale, best verbal response, oriented, 24 hours or more after hospital admission

  • R40.231

    Coma scale, best motor response, none

  • R40.2310

    Coma scale, best motor response, none, unspecified time

  • R40.2311

    Coma scale, best motor response, none, in the field [EMT or ambulance]

  • R40.2312

    Coma scale, best motor response, none, at arrival to emergency department

  • R40.2313

    Coma scale, best motor response, none, at hospital admission

  • R40.2314

    Coma scale, best motor response, none, 24 hours or more after hospital admission

  • R40.232

    Coma scale, best motor response, extension

  • R40.2320

    Coma scale, best motor response, extension, unspecified time

  • R40.2321

    Coma scale, best motor response, extension, in the field [EMT or ambulance]

  • R40.2322

    Coma scale, best motor response, extension, at arrival to emergency department

  • R40.2323

    Coma scale, best motor response, extension, at hospital admission

  • R40.2324

    Coma scale, best motor response, extension, 24 hours or more after hospital admission

  • R40.233

    Coma scale, best motor response, abnormal flexion

  • R40.2330

    Coma scale, best motor response, abnormal flexion, unspecified time

  • R40.2331

    Coma scale, best motor response, abnormal flexion, in the field [EMT or ambulance]

  • R40.2332

    Coma scale, best motor response, abnormal flexion, at arrival to emergency department

  • R40.2333

    Coma scale, best motor response, abnormal flexion, at hospital admission

  • R40.2334

    Coma scale, best motor response, abnormal flexion, 24 hours or more after hospital admission

  • R40.234

    Coma scale, best motor response, flexion withdrawal

  • R40.2340

    Coma scale, best motor response, flexion withdrawal, unspecified time

  • R40.2341

    Coma scale, best motor response, flexion withdrawal, in the field [EMT or ambulance]

  • R40.2342

    Coma scale, best motor response, flexion withdrawal, at arrival to emergency department

  • R40.2343

    Coma scale, best motor response, flexion withdrawal, at hospital admission

  • R40.2344

    Coma scale, best motor response, flexion withdrawal, 24 hours or more after hospital admission

  • R40.235

    Coma scale, best motor response, localizes pain

  • R40.2350

    Coma scale, best motor response, localizes pain, unspecified time

  • R40.2351

    Coma scale, best motor response, localizes pain, in the field [EMT or ambulance]

  • R40.2352

    Coma scale, best motor response, localizes pain, at arrival to emergency department

  • R40.2353

    Coma scale, best motor response, localizes pain, at hospital admission

  • R40.2354

    Coma scale, best motor response, localizes pain, 24 hours or more after hospital admission

  • R40.236

    Coma scale, best motor response, obeys commands

  • R40.2360

    Coma scale, best motor response, obeys commands, unspecified time

  • R40.2361

    Coma scale, best motor response, obeys commands, in the field [EMT or ambulance]

  • R40.2362

    Coma scale, best motor response, obeys commands, at arrival to emergency department

  • R40.2363

    Coma scale, best motor response, obeys commands, at hospital admission

  • R40.2364

    Coma scale, best motor response, obeys commands, 24 hours or more after hospital admission

  • R40.241

    Glasgow coma scale score 13-15

  • R40.2410

    Glasgow coma scale score 13-15, unspecified time

  • R40.2411

    Glasgow coma scale score 13-15, in the field [EMT or ambulance]

  • R40.2412

    Glasgow coma scale score 13-15, at arrival to emergency department

  • R40.2413

    Glasgow coma scale score 13-15, at hospital admission

  • R40.2414

    Glasgow coma scale score 13-15, 24 hours or more after hospital admission

  • R40.242

    Glasgow coma scale score 9-12

  • R40.2420

    Glasgow coma scale score 9-12, unspecified time

  • R40.2421

    Glasgow coma scale score 9-12, in the field [EMT or ambulance]

  • R40.2422

    Glasgow coma scale score 9-12, at arrival to emergency department

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