Chapter 18

R00–R99: Symptoms, Signs and Abnormal Clinical and Laboratory Findings

Symptoms, Signs and Abnormal Clinical and Laboratory Findings diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)
  • abnormal findings on antenatal screening of mother (O28.-)
  • certain conditions originating in the perinatal period (P04-P96)
  • signs and symptoms classified in the body system chapters
  • signs and symptoms of breast (N63, N64.5)
Internal Codes
  • R79.82

    Elevated C-reactive protein (CRP)

  • R79.83

    Abnormal findings of blood amino-acid level

  • R79.89

    Other specified abnormal findings of blood chemistry

  • R79.9

    Abnormal finding of blood chemistry, unspecified

  • R80.0

    Isolated proteinuria

  • R80.1

    Persistent proteinuria, unspecified

  • R80.2

    Orthostatic proteinuria, unspecified

  • R80.3

    Bence Jones proteinuria

  • R80.8

    Other proteinuria

  • R80.9

    Proteinuria, unspecified

  • R81

    Glycosuria

  • R82.0

    Chyluria

  • R82.1

    Myoglobinuria

  • R82.2

    Biliuria

  • R82.3

    Hemoglobinuria

  • R82.4

    Acetonuria

  • R82.5

    Elevated urine levels of drugs, medicaments and biological substances

  • R82.6

    Abnormal urine levels of substances chiefly nonmedicinal as to source

  • R82.71

    Bacteriuria

  • R82.79

    Other abnormal findings on microbiological examination of urine

  • R82.81

    Pyuria

  • R82.89

    Other abnormal findings on cytological and histological examination of urine

  • R82.90

    Unspecified abnormal findings in urine

  • R82.91

    Other chromoabnormalities of urine

  • R82.991

    Hypocitraturia

  • R82.992

    Hyperoxaluria

  • R82.993

    Hyperuricosuria

  • R82.994

    Hypercalciuria

  • R82.998

    Other abnormal findings in urine

  • R83.0

    Abnormal level of enzymes in cerebrospinal fluid

  • R83.1

    Abnormal level of hormones in cerebrospinal fluid

  • R83.2

    Abnormal level of other drugs, medicaments and biological substances in cerebrospinal fluid

  • R83.3

    Abnormal level of substances chiefly nonmedicinal as to source in cerebrospinal fluid

  • R83.4

    Abnormal immunological findings in cerebrospinal fluid

  • R83.5

    Abnormal microbiological findings in cerebrospinal fluid

  • R83.6

    Abnormal cytological findings in cerebrospinal fluid

  • R83.8

    Other abnormal findings in cerebrospinal fluid

  • R83.9

    Unspecified abnormal finding in cerebrospinal fluid

  • R84.0

    Abnormal level of enzymes in specimens from respiratory organs and thorax

  • R84.1

    Abnormal level of hormones in specimens from respiratory organs and thorax

  • R84.2

    Abnormal level of other drugs, medicaments and biological substances in specimens from respiratory organs and thorax

  • R84.3

    Abnormal level of substances chiefly nonmedicinal as to source in specimens from respiratory organs and thorax

  • R84.4

    Abnormal immunological findings in specimens from respiratory organs and thorax

  • R84.5

    Abnormal microbiological findings in specimens from respiratory organs and thorax

  • R84.6

    Abnormal cytological findings in specimens from respiratory organs and thorax

  • R84.7

    Abnormal histological findings in specimens from respiratory organs and thorax

  • R84.8

    Other abnormal findings in specimens from respiratory organs and thorax

  • R84.9

    Unspecified abnormal finding in specimens from respiratory organs and thorax

  • R85.0

    Abnormal level of enzymes in specimens from digestive organs and abdominal cavity

  • R85.1

    Abnormal level of hormones in specimens from digestive organs and abdominal cavity

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