Chapter 18

R00–R99: Symptoms, Signs and Abnormal Clinical and Laboratory Findings

Symptoms, Signs and Abnormal Clinical and Laboratory Findings diagnostic classification updated for 2026.

Chapter Instructions

Excludes2(Not included here. Code separately if applicable.)
  • abnormal findings on antenatal screening of mother (O28.-)
  • certain conditions originating in the perinatal period (P04-P96)
  • signs and symptoms classified in the body system chapters
  • signs and symptoms of breast (N63, N64.5)
Internal Codes
  • R52

    Pain, unspecified

  • R53.0

    Neoplastic (malignant) related fatigue

  • R53.1

    Weakness

  • R53.2

    Functional quadriplegia

  • R53.81

    Other malaise

  • R53.82

    Chronic fatigue, unspecified

  • R53.83

    Other fatigue

  • R54

    Age-related physical debility

  • R55

    Syncope and collapse

  • R56.00

    Simple febrile convulsions

  • R56.01

    Complex febrile convulsions

  • R56.1

    Post traumatic seizures

  • R56.9

    Unspecified convulsions

  • R57.0

    Cardiogenic shock

  • R57.1

    Hypovolemic shock

  • R57.8

    Other shock

  • R57.9

    Shock, unspecified

  • R58

    Hemorrhage, not elsewhere classified

  • R59.0

    Localized enlarged lymph nodes

  • R59.1

    Generalized enlarged lymph nodes

  • R59.9

    Enlarged lymph nodes, unspecified

  • R60.0

    Localized edema

  • R60.1

    Generalized edema

  • R60.9

    Edema, unspecified

  • R61

    Generalized hyperhidrosis

  • R62.0

    Delayed milestone in childhood

  • R62.50

    Unspecified lack of expected normal physiological development in childhood

  • R62.51

    Failure to thrive (child)

  • R62.52

    Short stature (child)

  • R62.59

    Other lack of expected normal physiological development in childhood

  • R62.7

    Adult failure to thrive

  • R63.0

    Anorexia

  • R63.1

    Polydipsia

  • R63.2

    Polyphagia

  • R63.30

    Feeding difficulties, unspecified

  • R63.31

    Pediatric feeding disorder, acute

  • R63.32

    Pediatric feeding disorder, chronic

  • R63.39

    Other feeding difficulties

  • R63.4

    Abnormal weight loss

  • R63.5

    Abnormal weight gain

  • R63.6

    Underweight

  • R63.8

    Other symptoms and signs concerning food and fluid intake

  • R64

    Cachexia

  • R65.10

    Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction

  • R65.11

    Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction

  • R65.20

    Severe sepsis without septic shock

  • R65.21

    Severe sepsis with septic shock

  • R68.0

    Hypothermia, not associated with low environmental temperature

  • R68.11

    Excessive crying of infant (baby)

  • R68.12

    Fussy infant (baby)

PreviousPage 11 of 16Next