O21.1

Billable

ChapterO00–O9A

Ranksubcategory

Official Description

Hyperemesis gravidarum with metabolic disturbance

Metadata & Insights

•2026 ICD-10-CM Edition - Effective October 1, 2025.
•Billable/specific code (valid for reimbursement).
•Chapter 15: Pregnancy, Childbirth and the Puerperium (O00-O9A).

Instructional Notes

Includes

Hyperemesis gravidarum, starting before the end of the 20th week of gestation, with metabolic disturbance such as carbohydrate depletion
Hyperemesis gravidarum, starting before the end of the 20th week of gestation, with metabolic disturbance such as dehydration
Hyperemesis gravidarum, starting before the end of the 20th week of gestation, with metabolic disturbance such as electrolyte imbalance

General instructions are available for the parent sections:

View CH15 Notes View O20-O29 Notes

Clinical Hierarchy

CH15Pregnancy, childbirth and the puerperium (O00-O9A)

O20-O29Other maternal disorders predominantly related to pregnancy (O20-O29)

O21Excessive vomiting in pregnancy

O21.1Hyperemesis gravidarum with metabolic disturbance

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to O21.1:

blockO20-O29

Other maternal disorders predominantly related to pregnancy (O20-O29)

View context instructions

chapterCH15

Pregnancy, childbirth and the puerperium (O00-O9A)

View context instructions

Alphabetic Index Mentions

These are Diagnosis Index lookup paths that route to O21.1. Use them as entry terms for search, then confirm final coding instructions in the Tabular List and notes above.

6 raw paths

Hyperemesis5 unique routes

gravidarum (mild)(5 variants)

severe (with metabolic disturbance)→O21.1

with(4 variants)

carbohydrate depletion→O21.1

dehydration→O21.1

electrolyte imbalance→O21.1

metabolic disturbance→O21.1

Imbalance1 unique routes

electrolyte

due to hyperemesis gravidarum→O21.1