C88

Non-Billable
ChapterC00–D49
Rankcategory
Official Description

Malignant immunoproliferative diseases and certain other B-cell lymphomas

Metadata & Insights
  • •2026 ICD-10-CM Edition - Effective October 1, 2025.
  • •Non-billable category (requires more specific sub-code).
  • •Chapter 2: Neoplasms (C00-D49).

C81-C96 Parent Instructions

Excludes2(Not included here)
  • Kaposi's sarcoma of lymph nodes (C46.3)
  • secondary and unspecified neoplasm of lymph nodes (C77.-)
  • secondary neoplasm of bone marrow (C79.52)
  • secondary neoplasm of spleen (C78.89)

Instructional Notes

Excludes1(Not coded here)
  • B-cell lymphoma, unspecified (C85.1-)
  • personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)

Clinical Hierarchy

CH2Neoplasms (C00-D49)
C81-C96Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)
C88Malignant immunoproliferative diseases and certain other B-cell lymphomas
C88.0Waldenström macroglobulinemia
C88.2Heavy chain disease
C88.3Immunoproliferative small intestinal disease
C88.4Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
C88.8Other malignant immunoproliferative diseases
C88.9Malignant immunoproliferative disease, unspecified

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to C88:

blockC81-C96
Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)
View context instructions

Alphabetic Index Mentions

These are Diagnosis Index lookup paths that route to C88. Use them as entry terms for search, then confirm final coding instructions in the Tabular List and notes above.

25 raw paths
Disease, diseased11 unique routes
alpha heavy chain→C88
Franklin→C88
gamma heavy chain→C88
heavy chain NEC→C88(4 variants)
alpha→C88
gamma→C88
mu→C88
immunoproliferative (malignant)→C88(3 variants)
small intestinal→C88
specified NEC→C88
mu heavy chain disease→C88
Disorder (of)1 unique routes
glomerular (in)
Waldenström macroglobulinemia→C88
Franklin disease1 unique routes
Direct index entry→C88
Glomerulonephritis1 unique routes
in (due to)
Waldenström macroglobulinemia→C88
Lymphoma (of) (malignant)9 unique routes
BALT→C88
bronchial-associated lymphoid tissue [BALT-lymphoma]→C88
extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]→C88
lymphoplasmacytic
with IgM-production→C88
MALT→C88
Mediterranean→C88
mucosa-associated lymphoid tissue [MALT-lymphoma]→C88
SALT→C88
skin-associated lymphoid tissue [SALT-lymphoma]→C88
Macroglobulinemia (idiopathic) (primary)2 unique routes
Direct index entry→C88
Waldenström→C88

MS-DRG Classification

2026

No direct MS-DRG triggers identified.

Cross Reference

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