R85.81

Billable

ChapterR00–R99

Ranksubcategory

Official Description

Anal high risk human papillomavirus (HPV) DNA test positive

Metadata & Insights

•2026 ICD-10-CM Edition - Effective October 1, 2025.
•Billable/specific code (valid for reimbursement).
•Chapter 18: Symptoms, Signs and Abnormal Clinical and Laboratory Findings (R00-R99).

Instructional Notes

Excludes1(Not coded here)

anogenital warts due to human papillomavirus (HPV) (A63.0)
condyloma acuminatum (A63.0)

General instructions are available for the parent sections:

View CH18 Notes View R83-R89 Notes View R85 Notes

Clinical Hierarchy

CH18Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)

R83-R89Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis (R83-R89)

R85Abnormal findings in specimens from digestive organs and abdominal cavity

R85.8Other abnormal findings in specimens from digestive organs and abdominal cavity

R85.81Anal high risk human papillomavirus (HPV) DNA test positive

Applicable Ancestor Context

The following parent sections contain instructions or notes that apply to R85.81:

categoryR85

Abnormal findings in specimens from digestive organs and abdominal cavity

View context instructions

blockR83-R89

Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis (R83-R89)

View context instructions

chapterCH18

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)

View context instructions

Alphabetic Index Mentions

These are Diagnosis Index lookup paths that route to R85.81. Use them as entry terms for search, then confirm final coding instructions in the Tabular List and notes above.

2 raw paths

Abnormal, abnormality, abnormalities2 unique routes

cytology

anus

human papillomavirus (HPV) DNA test

high risk positive→R85.81

Papanicolaou (smear)

anus

human papillomavirus (HPV) DNA test

high risk positive→R85.81