Other and unspecified malignant neoplasms of lymphoid, hematopoietic and related tissue
In Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96), chapter 2: Neoplasms
11 billable codes under C96: all are a CC; all map to HCC 21 (Lymphoma and Other Cancers).A CC or MCC (major CC) is a secondary diagnosis that raises the MS-DRG payment. An HCC counts toward a Medicare Advantage patient's risk score.
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Instructional notes
Excludes1: not coded here, use a different code
- personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)
Also applies, from Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)
These notes sit on C81-C96 and apply to every code under it, including C96.
Official coding guidelines
From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.
Rules for coding benign and malignant neoplasms: using the Neoplasm Table, sequencing primary and secondary sites, treatment encounters, complications, and current cancer versus personal history.
- Admission/Encounter for treatment of primary site (page 33)
- Admission/Encounter for treatment of secondary site (page 33)
- Coding and sequencing of complications (page 34)
- Primary malignancy previously excised (page 34)
- Admissions/Encounters involving antineoplastic chemotherapy, immunotherapy and radiation therapy (page 35)
- Admission/encounter to determine extent of malignancy (page 36)
- Symptoms, signs, and abnormal findings listed in Chapter 18 associated with neoplasms (page 36)
- Admission/encounter for pain control/management (page 36)
All codes under C96
C96 can't be used on a claim. Pick a billable code below; grey headings group them.
- C96.0Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis
- C96.2Malignant mast cell neoplasm
- C96.20Malignant mast cell neoplasm, unspecified
- C96.21Aggressive systemic mastocytosis
- C96.22Mast cell sarcoma
- C96.29Other malignant mast cell neoplasm
- C96.4Sarcoma of dendritic cells (accessory cells)
- C96.5Multifocal and unisystemic Langerhans-cell histiocytosis
- C96.6Unifocal Langerhans-cell histiocytosis
- C96.9Malignant neoplasm of lymphoid, hematopoietic and related tissue, unspecified
- C96.AHistiocytic sarcoma
- C96.ZOther specified malignant neoplasms of lymphoid, hematopoietic and related tissue
C96 MS-DRGs
As the principal diagnosis, the billable codes under C96 group to these 13 MS-DRGs (v44.0). Which one applies depends on procedures performed, secondary diagnoses (CC/MCC), and the patient's age and discharge status.
- DRG 820 Lymphoma and Leukemia with Major O.R. Procedures with MCC (3 of 11 codes)
- DRG 821 Lymphoma and Leukemia with Major O.R. Procedures with CC (3 of 11 codes)
- DRG 822 Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC (3 of 11 codes)
- DRG 823 Lymphoma and Non-Acute Leukemia with Other Procedures with MCC (3 of 11 codes)
- DRG 824 Lymphoma and Non-Acute Leukemia with Other Procedures with CC (3 of 11 codes)
- DRG 825 Lymphoma and Non-Acute Leukemia with Other Procedures without CC/MCC (3 of 11 codes)
- DRG 840 Lymphoma and Non-Acute Leukemia with MCC (3 of 11 codes)
- DRG 841 Lymphoma and Non-Acute Leukemia with CC (3 of 11 codes)
- DRG 842 Lymphoma and Non-Acute Leukemia without CC/MCC (3 of 11 codes)
- DRG 642 Inborn and Other Disorders of Metabolism (2 of 11 codes)
- DRG 146 Ear, Nose, Mouth and Throat Malignancy with MCC (1 of 11 codes)
- DRG 147 Ear, Nose, Mouth and Throat Malignancy with CC (1 of 11 codes)
- DRG 148 Ear, Nose, Mouth and Throat Malignancy without CC/MCC (1 of 11 codes)
Other codes that refer to C96
Notes on these codes point to C96.
- C76 Excludes1: malignant neoplasm of lymphoid, hematopoietic and related tissue (C81-C96)
- C77 Excludes1: malignant neoplasm of lymph nodes, specified as primary (C81-C86, C88, C96.-)
- D59.39 Code Also: malignant neoplasm (C00-C96)
- D84.81 Code First: malignant neoplasms (C00-C96)
- E08 Code First: malignant neoplasm (C00-C96)
- O9A.1 Includes: Conditions in C00-C96
- Z15.0 Code First: if applicable, any current malignant neoplasm (C00-C75, C81-C96)
- Z80.7 Includes: Conditions classifiable to C81-C90, C96.-
- Z85.79 Includes: Conditions classifiable to C88-C90, C96
About the condition
Plain-language background from MedlinePlus (National Library of Medicine), not coding guidance.
Leukemia
Leukemia is a term for cancers of the blood cells. Leukemia starts in blood-forming tissues such as the bone marrow. Your bone marrow makes the cells which will develop into white blood cells, red blood cells, and platelets. Each type of cell has a different job:
Read more about leukemia on MedlinePlusLymphoma
Lymphoma is a cancer of a part of the immune system called the lymph system. There are many types of lymphoma. One type is Hodgkin disease. The rest are called non-Hodgkin lymphomas.
Read more about lymphoma on MedlinePlusCode history
Valid since FY2016, when ICD-10-CM took effect on October 1, 2015. No changes since.
