All ICD10 Codes
C91Not billable, use a more specific code below

Lymphoid leukemia

In Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96), chapter 2: Neoplasms

27 billable codes under C91: all are a CC; all map to HCC 22 (Bladder, Colorectal, and Other Cancers), HCC 19 (Myelodysplastic Syndromes, Multiple Myeloma, and Other Cancers), HCC 18 (Cancer Metastatic to Bone, Other and Unspecified Metastatic Cancer; Acute Leukemia Except Myeloid) and 1 more HCCs.A CC or MCC (major CC) is a secondary diagnosis that raises the MS-DRG payment. An HCC counts toward a Medicare Advantage patient's risk score.

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Instructional notes

Excludes1: not coded here, use a different code

  • personal history of leukemia (Z85.6)

Also applies, from Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)

These notes sit on C81-C96 and apply to every code under it, including C91.

Excludes2: not included here, code separately if applicable

  • Kaposi's sarcoma of lymph nodes (C46.3)
  • secondary and unspecified neoplasm of lymph nodes (C77.-)
  • secondary neoplasm of bone marrow (C79.52)
  • secondary neoplasm of spleen (C78.89)

Official coding guidelines

From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.

Rules for coding benign and malignant neoplasms: using the Neoplasm Table, sequencing primary and secondary sites, treatment encounters, complications, and current cancer versus personal history.

Read Section I.C.2 (page 32), 12 more topics

All codes under C91

C91 can't be used on a claim. Pick a billable code below; grey headings group them.

C91 MS-DRGs

As the principal diagnosis, the billable codes under C91 group to these 16 MS-DRGs (v44.0). Which one applies depends on procedures performed, secondary diagnoses (CC/MCC), and the patient's age and discharge status.

Other codes that refer to C91

Notes on these codes point to C91.

  • D72.8 Excludes1: leukemia (C91-C95)
  • D72.825 Excludes1: leukemia (C91.-, C92.-, C93.-, C94.-, C95.-)
  • M36.1 Code First: leukemia (C91-C95)
  • N16 Code First: leukemia (C91-C95)
  • R50.81 Code First: leukemia (C91-C95)
  • T66 Excludes1: leukemia (C91-C95)
  • Z80.6 Includes: Conditions classifiable to C91-C95
  • Z85.6 Includes: Conditions classifiable to C91-C95

About the condition

Plain-language background from MedlinePlus (National Library of Medicine), not coding guidance.

Acute Lymphocytic Leukemia

Leukemia is a term for cancers of the blood cells. Leukemia starts in blood-forming tissues such as the bone marrow. Your bone marrow makes the cells which will develop into white blood cells, red blood cells, and platelets. Each type of cell has a different job:

Read more about acute lymphocytic leukemia on MedlinePlus

Chronic Lymphocytic Leukemia

Leukemia is a term for cancers of the blood cells. Leukemia starts in blood-forming tissues such as the bone marrow. Your bone marrow makes the cells which will develop into white blood cells, red blood cells, and platelets. Each type of cell has a different job:

Read more about chronic lymphocytic leukemia on MedlinePlus

Code history

Valid since FY2016, when ICD-10-CM took effect on October 1, 2015. No changes since.