Hodgkin lymphoma
In Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96), chapter 2: Neoplasms
77 billable codes under C81: all are a CC; all map to HCC 21 (Lymphoma and Other Cancers).A CC or MCC (major CC) is a secondary diagnosis that raises the MS-DRG payment. An HCC counts toward a Medicare Advantage patient's risk score.
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Instructional notes
Excludes1: not coded here, use a different code
- personal history of Hodgkin lymphoma (Z85.71)
Also applies, from Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)
These notes sit on C81-C96 and apply to every code under it, including C81.
Official coding guidelines
From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.
Rules for coding benign and malignant neoplasms: using the Neoplasm Table, sequencing primary and secondary sites, treatment encounters, complications, and current cancer versus personal history.
- Admission/Encounter for treatment of primary site (page 33)
- Admission/Encounter for treatment of secondary site (page 33)
- Coding and sequencing of complications (page 34)
- Primary malignancy previously excised (page 34)
- Admissions/Encounters involving antineoplastic chemotherapy, immunotherapy and radiation therapy (page 35)
- Admission/encounter to determine extent of malignancy (page 36)
- Symptoms, signs, and abnormal findings listed in Chapter 18 associated with neoplasms (page 36)
- Admission/encounter for pain control/management (page 36)
All codes under C81
C81 can't be used on a claim. Pick a billable code below; grey headings group them.
- C81.0Nodular lymphocyte predominant Hodgkin lymphoma
- C81.00Nodular lymphocyte predominant Hodgkin lymphoma, unspecified site
- C81.01Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of head, face, and neck
- C81.02Nodular lymphocyte predominant Hodgkin lymphoma, intrathoracic lymph nodes
- C81.03Nodular lymphocyte predominant Hodgkin lymphoma, intra-abdominal lymph nodes
- C81.04Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of axilla and upper limb
- C81.05Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
- C81.06Nodular lymphocyte predominant Hodgkin lymphoma, intrapelvic lymph nodes
- C81.07Nodular lymphocyte predominant Hodgkin lymphoma, spleen
- C81.08Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of multiple sites
- C81.09Nodular lymphocyte predominant Hodgkin lymphoma, extranodal and solid organ sites
- C81.0ANodular lymphocyte predominant Hodgkin lymphoma, in remission
- C81.1Nodular sclerosis Hodgkin lymphoma
- C81.10Nodular sclerosis Hodgkin lymphoma, unspecified site
- C81.11Nodular sclerosis Hodgkin lymphoma, lymph nodes of head, face, and neck
- C81.12Nodular sclerosis Hodgkin lymphoma, intrathoracic lymph nodes
- C81.13Nodular sclerosis Hodgkin lymphoma, intra-abdominal lymph nodes
- C81.14Nodular sclerosis Hodgkin lymphoma, lymph nodes of axilla and upper limb
- C81.15Nodular sclerosis Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
- C81.16Nodular sclerosis Hodgkin lymphoma, intrapelvic lymph nodes
- C81.17Nodular sclerosis Hodgkin lymphoma, spleen
- C81.18Nodular sclerosis Hodgkin lymphoma, lymph nodes of multiple sites
- C81.19Nodular sclerosis Hodgkin lymphoma, extranodal and solid organ sites
- C81.1ANodular sclerosis Hodgkin lymphoma, in remission
- C81.2Mixed cellularity Hodgkin lymphoma
- C81.20Mixed cellularity Hodgkin lymphoma, unspecified site
- C81.21Mixed cellularity Hodgkin lymphoma, lymph nodes of head, face, and neck
- C81.22Mixed cellularity Hodgkin lymphoma, intrathoracic lymph nodes
- C81.23Mixed cellularity Hodgkin lymphoma, intra-abdominal lymph nodes
- C81.24Mixed cellularity Hodgkin lymphoma, lymph nodes of axilla and upper limb
- C81.25Mixed cellularity Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
- C81.26Mixed cellularity Hodgkin lymphoma, intrapelvic lymph nodes
- C81.27Mixed cellularity Hodgkin lymphoma, spleen
- C81.28Mixed cellularity Hodgkin lymphoma, lymph nodes of multiple sites
- C81.29Mixed cellularity Hodgkin lymphoma, extranodal and solid organ sites
- C81.2AMixed cellularity Hodgkin lymphoma, in remission
- C81.3Lymphocyte depleted Hodgkin lymphoma
- C81.30Lymphocyte depleted Hodgkin lymphoma, unspecified site
- C81.31Lymphocyte depleted Hodgkin lymphoma, lymph nodes of head, face, and neck
- C81.32Lymphocyte depleted Hodgkin lymphoma, intrathoracic lymph nodes
- C81.33Lymphocyte depleted Hodgkin lymphoma, intra-abdominal lymph nodes
- C81.34Lymphocyte depleted Hodgkin lymphoma, lymph nodes of axilla and upper limb
- C81.35Lymphocyte depleted Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
- C81.36Lymphocyte depleted Hodgkin lymphoma, intrapelvic lymph nodes
- C81.37Lymphocyte depleted Hodgkin lymphoma, spleen
- C81.38Lymphocyte depleted Hodgkin lymphoma, lymph nodes of multiple sites
- C81.39Lymphocyte depleted Hodgkin lymphoma, extranodal and solid organ sites
- C81.3ALymphocyte depleted Hodgkin lymphoma, in remission
- C81.4Lymphocyte-rich Hodgkin lymphoma
- C81.40Lymphocyte-rich Hodgkin lymphoma, unspecified site
- C81.41Lymphocyte-rich Hodgkin lymphoma, lymph nodes of head, face, and neck
- C81.42Lymphocyte-rich Hodgkin lymphoma, intrathoracic lymph nodes
- C81.43Lymphocyte-rich Hodgkin lymphoma, intra-abdominal lymph nodes
- C81.44Lymphocyte-rich Hodgkin lymphoma, lymph nodes of axilla and upper limb
- C81.45Lymphocyte-rich Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
- C81.46Lymphocyte-rich Hodgkin lymphoma, intrapelvic lymph nodes
- C81.47Lymphocyte-rich Hodgkin lymphoma, spleen
- C81.48Lymphocyte-rich Hodgkin lymphoma, lymph nodes of multiple sites
- C81.49Lymphocyte-rich Hodgkin lymphoma, extranodal and solid organ sites
- C81.4ALymphocyte-rich Hodgkin lymphoma, in remission
- C81.7Other Hodgkin lymphoma
- C81.70Other Hodgkin lymphoma, unspecified site
- C81.71Other Hodgkin lymphoma, lymph nodes of head, face, and neck
- C81.72Other Hodgkin lymphoma, intrathoracic lymph nodes
- C81.73Other Hodgkin lymphoma, intra-abdominal lymph nodes
- C81.74Other Hodgkin lymphoma, lymph nodes of axilla and upper limb
- C81.75Other Hodgkin lymphoma, lymph nodes of inguinal region and lower limb
- C81.76Other Hodgkin lymphoma, intrapelvic lymph nodes
- C81.77Other Hodgkin lymphoma, spleen
- C81.78Other Hodgkin lymphoma, lymph nodes of multiple sites
- C81.79Other Hodgkin lymphoma, extranodal and solid organ sites
- C81.7AOther Hodgkin lymphoma, in remission
- C81.9Hodgkin lymphoma, unspecified
- C81.90Hodgkin lymphoma, unspecified, unspecified site
- C81.91Hodgkin lymphoma, unspecified, lymph nodes of head, face, and neck
- C81.92Hodgkin lymphoma, unspecified, intrathoracic lymph nodes
- C81.93Hodgkin lymphoma, unspecified, intra-abdominal lymph nodes
- C81.94Hodgkin lymphoma, unspecified, lymph nodes of axilla and upper limb
- C81.95Hodgkin lymphoma, unspecified, lymph nodes of inguinal region and lower limb
- C81.96Hodgkin lymphoma, unspecified, intrapelvic lymph nodes
- C81.97Hodgkin lymphoma, unspecified, spleen
- C81.98Hodgkin lymphoma, unspecified, lymph nodes of multiple sites
- C81.99Hodgkin lymphoma, unspecified, extranodal and solid organ sites
- C81.9AHodgkin lymphoma, unspecified, in remission
C81 MS-DRGs
As the principal diagnosis, the billable codes under C81 group to these 9 MS-DRGs (v44.0). Which one applies depends on procedures performed, secondary diagnoses (CC/MCC), and the patient's age and discharge status.
- DRG 820 Lymphoma and Leukemia with Major O.R. Procedures with MCC (70 of 77 codes)
- DRG 821 Lymphoma and Leukemia with Major O.R. Procedures with CC (70 of 77 codes)
- DRG 822 Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC (70 of 77 codes)
- DRG 823 Lymphoma and Non-Acute Leukemia with Other Procedures with MCC (70 of 77 codes)
- DRG 824 Lymphoma and Non-Acute Leukemia with Other Procedures with CC (70 of 77 codes)
- DRG 825 Lymphoma and Non-Acute Leukemia with Other Procedures without CC/MCC (70 of 77 codes)
- DRG 840 Lymphoma and Non-Acute Leukemia with MCC (70 of 77 codes)
- DRG 841 Lymphoma and Non-Acute Leukemia with CC (70 of 77 codes)
- DRG 842 Lymphoma and Non-Acute Leukemia without CC/MCC (70 of 77 codes)
Other codes that refer to C81
Notes on these codes point to C81.
- C26.1 Excludes1: Hodgkin lymphoma (C81.-)
- C76 Excludes1: malignant neoplasm of lymphoid, hematopoietic and related tissue (C81-C96)
- C77 Excludes1: malignant neoplasm of lymph nodes, specified as primary (C81-C86, C88, C96.-)
- Z15.0 Code First: if applicable, any current malignant neoplasm (C00-C75, C81-C96)
- Z80.7 Includes: Conditions classifiable to C81-C90, C96.-
- Z85.71 Includes: Conditions classifiable to C81
About the condition
Plain-language background from MedlinePlus (National Library of Medicine), not coding guidance.
Hodgkin Lymphoma
Hodgkin lymphoma, also called Hodgkin disease, is a type of cancer that develops in the lymph system. Your lymph system is part of your immune system. It helps protect your body from infection and disease.
Read more about hodgkin lymphoma on MedlinePlusCode history
Valid since FY2016, when ICD-10-CM took effect on October 1, 2015. No changes since.
