Infectious mononucleosis
In Other viral diseases (B25-B34), chapter 1: Certain Infectious and Parasitic Diseases
16 billable codes under B27: none are a CC or MCC; none map to an HCC.
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Instructional notes
Includes: conditions that are coded here
- glandular fever
- monocytic angina
- Pfeiffer's disease
Official coding guidelines
From the ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027 (CMS and NCHS). Links open the PDF at the right page.
Rules for coding infections and parasitic diseases, including HIV, organism and drug resistance codes, sepsis and septic shock, MRSA, Zika, and COVID-19.
- Human Immunodeficiency Virus (HIV) Infections (page 19)
- Infectious agents as the cause of diseases classified to other chapters (page 22)
- Infections resistant to antibiotics (page 22)
- Sepsis, Severe Sepsis, and Septic Shock (page 23)
- Methicillin Resistant Staphylococcus aureus (MRSA) Conditions (page 27)
- Zika virus infections (page 28)
- Coronavirus infections (page 28)
All codes under B27
B27 can't be used on a claim. Pick a billable code below; grey headings group them.
- B27.0Gammaherpesviral mononucleosis
- B27.00Gammaherpesviral mononucleosis without complication
- B27.01Gammaherpesviral mononucleosis with polyneuropathy
- B27.02Gammaherpesviral mononucleosis with meningitis
- B27.09Gammaherpesviral mononucleosis with other complications
- B27.1Cytomegaloviral mononucleosis
- B27.10Cytomegaloviral mononucleosis without complications
- B27.11Cytomegaloviral mononucleosis with polyneuropathy
- B27.12Cytomegaloviral mononucleosis with meningitis
- B27.19Cytomegaloviral mononucleosis with other complication
- B27.8Other infectious mononucleosis
- B27.80Other infectious mononucleosis without complication
- B27.81Other infectious mononucleosis with polyneuropathy
- B27.82Other infectious mononucleosis with meningitis
- B27.89Other infectious mononucleosis with other complication
- B27.9Infectious mononucleosis, unspecified
- B27.90Infectious mononucleosis, unspecified without complication
- B27.91Infectious mononucleosis, unspecified with polyneuropathy
- B27.92Infectious mononucleosis, unspecified with meningitis
- B27.99Infectious mononucleosis, unspecified with other complication
B27 MS-DRGs
As the principal diagnosis, all 16 billable codes under B27 group to MS-DRG 865 or 866 (v44.0). Which one applies depends on procedures performed, secondary diagnoses (CC/MCC), and the patient's age and discharge status.
Other codes that refer to B27
Notes on these codes point to B27.
About the condition
Plain-language background from MedlinePlus (National Library of Medicine), not coding guidance.
Infectious Mononucleosis
Infectious mononucleosis (mono) is a disease caused by viruses.The most common cause is the Epstein-Barr virus (EBV). Mono is contagious, which means it can spread from person to person. It is common among teenagers and young adults, especially college students.
Read more about infectious mononucleosis on MedlinePlusCode history
Valid since FY2016, when ICD-10-CM took effect on October 1, 2015. No changes since.